Lai, D., Kapoor, M., Wetherill, L., Schwandt, M., Ramchandani, V. A., Goldman, D., Chao, M., Almasy, L., Bucholz, K., Hart, R. P., Kamarajan, C., Meyers, J. L., Nurnberger, J. I., Tischfield, J., Edenberg, H. J., Schuckit, M., Goate, A., Scott, D. M., Porjesz, B., Agrawal, A., & Foroud, T. (2020). Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. PubMed
Scarnati, M. S., Boreland, A. J., Joel, M., Hart, R. P., & Pang, Z. P. (2020). Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. Alcohol (Fayetteville, N.Y.). PubMed
Halikere, A., Popova, D., Scarnati, M. S., Hamod, A., Swerdel, M. R., Moore, J. C., Tischfield, J. A., Hart, R. P., & Pang, Z. P. (2020). Modelling the single most common SNP in OPRM1 (A118G) using human neurons generated from two sets of independently targeted isogenic stem cell lines. Molecular psychiatry, 25, 1355. PubMed
Xu, R., Li, X., Boreland, A. J., Posyton, A., Kwan, K., Hart, R. P., & Jiang, P. (2020). Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain. Nature communications, 11, 1577. PubMed
Popovitchenko, T., Park, Y., Page, N. F., Luo, X., Krsnik, Z., Liu, Y., Salamon, I., Stephenson, J. D., Kraushar, M. L., Volk, N. L., Patel, S. M., Wijeratne, H. R. S., Li, D., Suthar, K. S., Wach, A., Sun, M., Arnold, S. J., Akamatsu, W., Okano, H., Paillard, L., Zhang, H., Buyske, S., Kostovic, I., De Rubeis, S., Hart, R. P., & Rasin, M. R. (2020). Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development. Nature communications, 11, 1674. PubMed
Fantuzzo, J. A., Robles, D. A., Mirabella, V. R., Hart, R. P., Pang, Z. P., & Zahn, J. D. (2020). Development of a high-throughput arrayed neural circuitry platform using human induced neurons for drug screening applications. Lab on a chip. PubMed
Halikere, A., Popova, D., Scarnati, M. S., Hamod, A., Swerdel, M. R., Moore, J. C., Tischfield, J. A., Hart, R. P., & Pang, Z. P. (2019). Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons. Molecular psychiatry. PubMed
Gokhale, S., Lu, W., Zhu, S., Liu, Y., Hart, R. P., Rabinowitz, J. D., & Xie, P. (2019). Elevated Choline Kinase α-Mediated Choline Metabolism Supports the Prolonged Survival of TRAF3-Deficient B Lymphocytes. Journal of immunology (Baltimore, Md. : 1950). PubMed
Hart, R.P. (2019) Strategies for Integrating Single-Cell RNA Sequencing Results With Multiple Species. bioRxiv 671115; doi: https://doi.org/10.1101/671115
Chow, H. M., Cheng, A., Song, X., Swerdel, M. R., Hart, R. P., & Herrup, K. (2019). ATM is activated by ATP depletion and modulates mitochondrial function through NRF1. The Journal of cell biology 218: 909-928. PubMed
Xu, R., Brawner, A. T., Li, S., Liu, J. J., Kim, H., Xue, H., Pang, Z. P., Kim, W. Y., Hart, R. P., Liu, Y., & Jiang, P. (2019). OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Cell stem cell 24:908-926.e8. PubMed
Grudzien-Nogalska, E., Wu, Y., Jiao, X., Cui, H., Mateyak, M. K., Hart, R. P., Tong, L., & Kiledjian, M. (2019). Structural and mechanistic basis of mammalian Nudt12 RNA deNADding. Nature chemical biology, 15, 575-582. PubMed
Vajtay, T. J., Bandi, A., Upadhyay, A., Swerdel, M. R., Hart, R. P., Lee, C. R., & Margolis, D. J. (2019). Optogenetic and transcriptomic interrogation of enhanced muscle function in the paralyzed mouse whisker pad. Journal of neurophysiology 121(4):1491-1500. PubMed
Fantuzzo, J. A., Hart, R. P., Zahn, J. D., & Pang, Z. P. (2019). Compartmentalized Devices as Tools for Investigation of Human Brain Network Dynamics. Developmental dynamics : an official publication of the American Association of Anatomists, 248, 65-77. PubMed
Chow, H.-M., A. Cheng, X. Song, M.R. Swerdel, R.P. Hart, K.Herrup (2018) ATM is activated by ATP depletion and modulates mitochondrial function through NRF1. bioRxiv 414490; doi: https://doi.org/10.1101/414490
Zucco, A. J., Pozzo, V. D., Afinogenova, A., Hart, R. P., Devinsky, O., & D’Arcangelo, G. (2018). Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation. Molecular and cellular neurosciences, 92, 149-163. PubMed
Tiethof, A. K., Richardson, J. R., & Hart, R. P. (2018). Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells. Toxics, 6. PubMed
Fantuzzo, J.A., R. P. Hart, J. D. Zahn & Z. P. Pang (2018) Compartmentalized devices as tools for investigation of human brain network dynamics. Developmental Dynamics.https://doi.org/10.1002/dvdy.24665PubMed
McGowan, H., Mirabella, V. R., Hamod, A., Karakhanyan, A., Mlynaryk, N., Moore, J. C., Tischfield, J. A., Hart, R. P., & Pang, Z. P. (2018). hsa-let-7c miRNA Regulates Synaptic and Neuronal Function in Human Neurons. Frontiers in synaptic neuroscience, 10, 19. PubMed
Tiethof, A.K., J.R. Richardson & R.P. Hart (2018) Knockdown of butyrylcholinesterase but not inhibition by chlorpyrifos alters early differentiation mechanisms in human neural stem cells. bioRxiv https://doi.org/10.1101/354308
Prytkova, I., Goate, A., Hart, R. P., & Slesinger, P. A. (2018). Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells? Alcoholism, clinical and experimental research. PubMed
Li, W., Huang, Y., Sargsyan, D., Khor, T. O., Guo, Y., Shu, L., Yang, A. Y., Zhang, C., Paredes-Gonzalez, X., Verzi, M., Hart, R. P., & Kong, A. N. (2018). Epigenetic alterations in TRAMP mice: epigenome DNA methylation profiling using MeDIP-seq. Cell & bioscience, 8, 3. PubMed
Halikere, A., D. Popova, A. Hamod, M.R. Swerdel, J.C. Moore, J.A. Tischfield, R.P. Hart & Z.P. Pang (2018) Addiction associated N40D mu-opioid receptor variant modulates synaptic functions in human neurons. bioRxiv https://doi.org/10.1101/328898
Eid, A., Bihaqi, S. W., Hemme, C., Gaspar, J. M., Hart, R. P., & Zawia, N. H. (2018). Histone acetylation maps in aged mice developmentally exposed to lead: epigenetic drift and Alzheimer-related genes. Epigenomics, 10, 573-583. PubMed
Guo, Y., Wu, R., Gaspar, J. M., Sargsyan, D., Su, Z. Y., Zhang, C., Gao, L., Cheng, D., Li, W., Wang, C., Yin, R., Fang, M., Verzi, M. P., Hart, R. P., & Kong, A. N. (2018). DNA methylome and transcriptome alterations and cancer prevention by curcumin in colitis-accelerated colon cancer in mice. Carcinogenesis, 39, 669-680. PubMed
Chen, J., Chen, Y., Vail, G., Chow, H., Zhang, Y., Louie, L., Li, J., Hart, R. P., Plummer, M. R., & Herrup, K. (2017). Erratum to: The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment. Molecular neurodegeneration, 12, 4. PubMed
Guo, Y., Su, Z. Y., Zhang, C., Gaspar, J. M., Wang, R., Hart, R. P., Verzi, M. P., & Kong, A. N. (2017). Mechanisms of colitis-accelerated colon carcinogenesis and its prevention with the combination of aspirin and curcumin: Transcriptomic analysis using RNA-seq. Biochemical pharmacology, 135, 22-34. PubMed
Fantuzzo, J. A., Mirabella, V. R., Hamod, A. H., Hart, R. P., Zahn, J. D., & Pang, Z. P. (2017). Intellicount: High-Throughput Quantification of Fluorescent Synaptic Protein Puncta by Machine Learning. eNeuro, 4. PubMed
Gaspar, J. M., & Hart, R. P. (2017). DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data. BMC bioinformatics, 18, 528. PubMed
Fantuzzo, J. A., De Filippis, L., McGowan, H., Yang, N., Ng, Y. H., Halikere, A., Liu, J. J., Hart, R. P., Wernig, M., Zahn, J. D., & Pang, Z. P. (2017). μNeurocircuitry: Establishing in vitro models of neurocircuits with human neurons. Technology, 5, 87-97. PubMed
Li, Y., Hao, H., Swerdel, M. R., Cho, H. Y., Lee, K. B., Hart, R. P., Lyu, Y. L., & Cai, L. (2017). Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network. Journal of neuroscience research. PubMed
Jiao, X., Doamekpor, S. K., Bird, J. G., Nickels, B. E., Tong, L., Hart, R. P., & Kiledjian, M. (2017). 5′ End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding. Cell, 168, 1015-1027.e10. PubMed
Guo, Y., Su, Z. Y., Zhang, C., Gaspar, J. M., Wang, R., Hart, R. P., Verzi, M. P., & Kong, A. T. (2017). Mechanisms of colitis-accelerated colon carcinogenesis and its prevention with the combination of aspirin and curcumin: transcriptomic analysis using RNA-seq. Biochemical pharmacology, 135: 22-34. PubMed
Oni, E.N., A. Halikere, G. Li, A. J. Toro-Ramos, M. R. Swerdel, J. L. Verpeut, J. C. Moore, N. T. Bello, L. J. Bierut, A. Goate, J. A. Tischfield, Z. P. Pang & R. P. Hart (2016) Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele. Scientific Reports 6: 34341 PubMed
Oni, E.N. and R.P. Hart (2016) Bioinformatic Analysis of DNA Methylation in Neural Progenitor Cell Models of Alcohol Abuse. Current Pharmacology Reports, 2, 203.
Chen, J., Chen, Y., Vail, G., Chow, H., Zhang, Y., Louie, L., Li, J., Hart, R. P., Plummer, M. R., & Herrup, K. (2016). The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment. Molecular neurodegeneration, 11, 60. PubMed
Hart, R. P., & Goff, L. A. (2016). Long Noncoding RNAs: Central to Nervous System Development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. PubMed
Popovitchenko, T., Thompson, K., Viljetic, B., Jiao, X., Kontonyiannis, D.L., Kiledjian, M., Hart, R.P., Rasin, M.R. (2016) The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex. Scientific Reports, doi: 10.1038/srep28998PubMed
De Filippis, L., Halikere, A., McGowan, H., Moore, J. C., Tischfield, J. A., Hart, R. P., & Pang, Z. P. (2016). Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells. Molecular brain, 9, 51. PubMed
Carlson, A. L., Bennett, N. K., Francis, N. L., Halikere, A., Clarke, S., Moore, J. C., Hart, R. P., Paradiso, K., Wernig, M., Kohn, J., Pang, Z. P., & Moghe, P. V. (2016). Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds. Nature communications, 7, 10862. PubMed
Grudzien-Nogalska, E., Jiao, X., Song, M. G., Hart, R. P., & Kiledjian, M. (2016). Nudt3 is an mRNA decapping enzyme that modulates cell migration. RNA (New York, N.Y.), 22, 773-81. PubMed
Lin, L., Swerdel, M. R., Lazaropoulos, M. P., Hoffman, G. S., Toro-Ramos, A. J., Wright, J., Lederman, H., Chen, J., Moore, J. C., & Hart, R. P. (2015). Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. Stem cell reports, 5, 1097-108. PubMed
Jiang, D., Zhang, Y., Hart, R. P., Chen, J., Herrup, K., & Li, J. (2015). Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency. Brain : a journal of neurology. PubMed
Kraushar, M. L., Viljetic, B., Wijeratne, H. R., Thompson, K., Jiao, X., Pike, J. W., Medvedeva, V., Groszer, M., Kiledjian, M., Hart, R. P., & Rasin, M. R. (2015). Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 35, 10911-26. PubMed
Guo, Y., Lee, J. H., Shu, L., Huang, Y., Li, W., Zhang, C., Yang, A. Y., Boyanapalli, S. S., Perekatt, A., Hart, R. P., Verzi, M., & Kong, A. N. (2015). Association of aberrant DNA methylation in Apc(min/+) mice with the epithelial-mesenchymal transition and Wnt/ß-catenin pathways: genome-wide analysis using MeDIP-seq. Cell & bioscience, 5, 24. PubMed
Carmel, J. B., Young, W., & Hart, R. P. (2015). Flipping the transcriptional switch from myelin inhibition to axon growth in the CNS. Frontiers in molecular neuroscience, 8, 34. PubMed
Siddiq, M. M., Hannila, S. S., Carmel, J. B., Bryson, J. B., Hou, J., Nikulina, E., Willis, M. R., Mellado, W., Richman, E. L., Hilaire, M., Hart, R. P., & Filbin, M. T. (2015). Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System. The Journal of biological chemistry, 290, 16343-56. PubMed
Xie, P., Moore, C. R., Swerdel, M. R., & Hart, R. P. (2014). Transcriptomic profiling of splenic B lymphomas spontaneously developed in B cell-specific TRAF3-deficient mice. Genomics data, 2, 386-388. PubMed
Davila, J. L., Goff, L. A., Ricupero, C. L., Camarillo, C., Oni, E. N., Swerdel, M. R., Toro-Ramos, A. J., Li, J., & Hart, R. P. (2014). A positive feedback mechanism that regulates expression of miR-9 during neurogenesis. PloS one, 9, e94348. PubMed
Yang, A. Y., Lee, J. H., Shu, L., Zhang, C., Su, Z. Y., Lu, Y., Huang, M. T., Ramirez, C., Pung, D., Huang, Y., Verzi, M., Hart, R. P., & Kong, A. N. (2014). Genome-wide analysis of DNA methylation in UVB- and DMBA/TPA-induced mouse skin cancer models. Life sciences, 113, 45-54. PubMed
Edwards, S., Baron, J., Moore, C. R., Liu, Y., Perlman, D. H., Hart, R. P., & Xie, P. (2014). Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes. Journal of hematology & oncology, 7, 56.
Kraushar, M. L., Thompson, K., Wijeratne, H. R., Viljetic, B., Sakers, K., Marson, J. W., Kontoyiannis, D. L., Buyske, S., Hart, R. P., & Rasin, M. R. (2014). Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R. Proceedings of the National Academy of Sciences of the United States of America, 111, E3815-24. PubMed
Ricupero, C. L., Swerdel, M. R., & Hart, R. P. (2013). Epigenome analysis of pluripotent stem cells. Methods in molecular biology (Clifton, N.J.), 997, 203-16. PubMed
Li, J., Hart, R. P., Mallimo, E. M., Swerdel, M. R., Kusnecov, A. W., & Herrup, K. (2013). EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia. Nature neuroscience, 16, 1745-53. PubMed
Sauvageau, M., Goff, L. A., Lodato, S., Bonev, B., Groff, A. F., Gerhardinger, C., Sanchez-Gomez, D. B., Hacisuleyman, E., Li, E., Spence, M., Liapis, S. C., Mallard, W., Morse, M., Swerdel, M. R., D’Ecclessis, M. F., Moore, J. C., Lai, V., Gong, G., Yancopoulos, G. D., Frendewey, D., Kellis, M., Hart, R. P., Valenzuela, D. M., Arlotta, P., & Rinn, J. L. (2013). Multiple knockout mouse models reveal lincRNAs are required for life and brain development. eLife, 2, e01749. PubMed
DeBoer, E. M., Kraushar, M. L., Hart, R. P., & Rasin, M. R. (2013). Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons. Neuroscience, 248, 499-528. PubMed
Hannila, S. S., Siddiq, M. M., Carmel, J. B., Hou, J., Chaudhry, N., Bradley, P. M., Hilaire, M., Richman, E. L., Hart, R. P., & Filbin, M. T. (2013). Secretory Leukocyte Protease Inhibitor Reverses Inhibition by CNS Myelin, Promotes Regeneration in the Optic Nerve, and Suppresses Expression of the Transforming Growth Factor-ß Signaling Protein Smad2. The Journal of neuroscience : the official journal of the Society for Neuroscience, 33, 5138-51. PubMed
Komlos, D., Mann, K. D., Zhuo, Y., Ricupero, C. L., Hart, R. P., Liu, A. Y., & Firestein, B. L. (2013). Glutamate dehydrogenase 1 and SIRT4 regulate glial development. Glia, 61, 394-408. PubMed
Mahishi, L. H., Hart, R. P., Lynch, D. R., & Ratan, R. R. (2012). miR-886-3p levels are elevated in Friedreich ataxia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32, 9369-73.
Pichardo-Casas, I., Goff, L. A., Swerdel, M. R., Athie, A., Davila, J., Ramos-Brossier, M., Lapid-Volosin, M., Friedman, W. J., Hart, R. P., & Vaca, L. (2012). Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation. Brain research, 1436, 20-33.
Li, H., Hader, A. T., Han, Y. R., Wong, J. A., Babiarz, J., Ricupero, C. L., Godfrey, S. B., Corradi, J. P., Fennell, M., Hart, R. P., Plummer, M. R., & Grumet, M. (2012). Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture. Developmental neurobiology, 72, 805-20. PubMed
Li, J., Chen, J., Ricupero, C. L., Hart, R. P., Schwartz, M. S., Kusnecov, A., & Herrup, K. (2012). Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nature medicine, 18, 783-90. PubMed
Ma, L., Yu, Y. M., Guo, Y., Hart, R. P., & Schachner, M. (2012). Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish. The European journal of neuroscience, 35, 353-65. PubMed
Camarillo, C., Swerdel, M., & Hart, R. P. (2011). Comparison of microarray and quantitative real-time PCR methods for measuring MicroRNA levels in MSC cultures. Methods in molecular biology (Clifton, N.J.), 698, 419-29. PubMed
Yu, Y. M., Gibbs, K. M., Davila, J., Campbell, N., Sung, S., Todorova, T. I., Otsuka, S., Sabaawy, H. E., Hart, R. P., & Schachner, M. (2011). MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. The European journal of neuroscience, 33, 1587-97. PubMed
Guo, Y., Ma, L., Cristofanilli, M., Hart, R. P., Hao, A., & Schachner, M. (2011). Transcription factor Sox11b is involved in spinal cord regeneration in adult zebrafish. Neuroscience, 172, 329-41. PubMed
Moore, J. C., Atze, K., Yeung, P. L., Toro-Ramos, A. J., Camarillo, C., Thompson, K., Ricupero, C. L., Brenneman, M. A., Cohen, R. I., & Hart, R. P. (2010). Efficient, high-throughput transfection of human embryonic stem cells. Stem cell research & therapy, 1, 23. PubMed
Lakshmipathy, U., Davila, J., & Hart, R. P. (2010). miRNA in pluripotent stem cells. Regenerative medicine, 5, 545-55. PubMed
Bail, S., Swerdel, M., Liu, H., Jiao, X., Goff, L. A., Hart, R. P., & Kiledjian, M. (2010). Differential regulation of microRNA stability. RNA (New York, N.Y.), 16, 1032-9. PubMed
Moore, J. C., Sadowy, S., Alikani, M., Toro-Ramos, A. J., Swerdel, M. R., Hart, R. P., & Cohen, R. I. (2010). A high-resolution molecular-based panel of assays for identification and characterization of human embryonic stem cell lines. Stem cell research, 4, 92-106. PubMed
Goff, L. A., Davila, J., Swerdel, M. R., Moore, J. C., Cohen, R. I., Wu, H., Sun, Y. E., & Hart, R. P. (2009). Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PloS one, 4, e7192. PubMed
Chang, Y. W., Goff, L. A., Li, H., Kane-Goldsmith, N., Tzatzalos, E., Hart, R. P., Young, W., & Grumet, M. (2009). Rapid induction of genes associated with tissue protection and neural development in contused adult spinal cord after radial glial cell transplantation. Journal of neurotrauma, 26, 979-93. PubMed
Li, H., Han, Y. R., Bi, C., Davila, J., Goff, L. A., Thompson, K., Swerdel, M., Camarillo, C., Ricupero, C. L., Hart, R. P., Plummer, M. R., & Grumet, M. (2008). Functional differentiation of a clone resembling embryonic cortical interneuron progenitors. Developmental neurobiology, 68, 1549-64. PubMed
Goff, L. A., Boucher, S., Ricupero, C. L., Fenstermacher, S., Swerdel, M., Chase, L. G., Adams, C. C., Chesnut, J., Lakshmipathy, U., & Hart, R. P. (2008). Differentiating human multipotent mesenchymal stromal cells regulate microRNAs: prediction of microRNA regulation by PDGF during osteogenesis. Experimental hematology, 36, 1354-1369. PubMed
Li, H., Chang, Y. W., Mohan, K., Su, H. W., Ricupero, C. L., Baridi, A., Hart, R. P., & Grumet, M. (2008). Activated Notch1 maintains the phenotype of radial glial cells and promotes their adhesion to laminin by upregulating nidogen. Glia, 56, 646-58. PubMed
Goff, L. A., Davila, J., Jörnsten, R., Keles, S., & Hart, R. P. (2007). Bioinformatic analysis of neural stem cell differentiation. Journal of biomolecular techniques : JBT, 18, 205-12. PubMed
Porter, J. F., Sharma, S., Wilson, D. L., Kappil, M. A., Hart, R. P., & Denhardt, D. T. (2005). Tissue inhibitor of metalloproteinases-1 stimulates gene expression in MDA-MB-435 human breast cancer cells by means of its ability to inhibit metalloproteinases. Breast cancer research and treatment, 94, 185-93. PubMed
Goff, L. A., Yang, M., Bowers, J., Getts, R. C., Padgett, R. W., & Hart, R. P. (2005). Rational probe optimization and enhanced detection strategy for microRNAs using microarrays. RNA biology, 2, 93-100. PubMed
Jones, T. B., Hart, R. P., & Popovich, P. G. (2005). Molecular control of physiological and pathological T-cell recruitment after mouse spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience, 25, 6576-83.
Goff, L. A., Bowers, J., Schwalm, J., Howerton, K., Getts, R. C., & Hart, R. P. (2004). Evaluation of sense-strand mRNA amplification by comparative quantitative PCR. BMC genomics, 5, 76. PubMed
Hu, R., Hebbar, V., Kim, B. R., Chen, C., Winnik, B., Buckley, B., Soteropoulos, P., Tolias, P., Hart, R. P., & Kong, A. N. (2004). In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat. The Journal of pharmacology and experimental therapeutics, 310, 263-71. PubMed
Pan, J. Z., Jörnsten, R., & Hart, R. P. (2004). Screening anti-inflammatory compounds in injured spinal cord with microarrays: a comparison of bioinformatics analysis approaches. Physiological genomics, 17, 201-14. PubMed
Weeks, J., & Hart, R. P. (2004). SCI-Base: an open-source spinal cord injury animal experimentation database. Lab animal, 33, 35-41. PubMed
Carmel, J. B., Kakinohana, O., Mestril, R., Young, W., Marsala, M., & Hart, R. P. (2004). Mediators of ischemic preconditioning identified by microarray analysis of rat spinal cord. Experimental neurology, 185, 81-96. PubMed
Li, H., Berlin, Y., Hart, R. P., & Grumet, M. (2003). Microtubules are critical for radial glial morphology: possible regulation by MAPs and MARKs. Glia, 44, 37-46. PubMed
Pan, J. Z., Ni, L., Sodhi, A., Aguanno, A., Young, W., & Hart, R. P. (2002). Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion. Journal of neuroscience research, 68, 315-22. PubMed
Nesic, O., Svrakic, N. M., Xu, G. Y., McAdoo, D., Westlund, K. N., Hulsebosch, C. E., Ye, Z., Galante, A., Soteropoulos, P., Tolias, P., Young, W., Hart, R. P., & Perez-Polo, J. R. (2002). DNA microarray analysis of the contused spinal cord: effect of NMDA receptor inhibition. Journal of neuroscience research, 68, 406-23.
Jones, T. B., Basso, D. M., Sodhi, A., Pan, J. Z., Hart, R. P., MacCallum, R. C., Lee, S., Whitacre, C. C., & Popovich, P. G. (2002). Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 22, 2690-700. PubMed
Carmel, J. B., Galante, A., Soteropoulos, P., Tolias, P., Recce, M., Young, W., & Hart, R. P. (2001). Gene expression profiling of acute spinal cord injury reveals spreading inflammatory signals and neuron loss. Physiological genomics, 7, 201-13. PubMed
Kim, W. K., Kan, Y., Ganea, D., Hart, R. P., Gozes, I., & Jonakait, G. M. (2000). Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience, 20, 3622-30. PubMed
Bai, Y., & Hart, R. P. (1998). Cultured sympathetic neurons express functional interleukin-1 receptors. Journal of neuroimmunology, 91, 43-54. PubMed
Carlson, C. D., Bai, Y., Ding, M., Jonakait, G. M., & Hart, R. P. (1996). Interleukin-1 involvement in the induction of leukemia inhibitory factor mRNA expression following axotomy of sympathetic ganglia. Journal of neuroimmunology, 70, 181-90. PubMed
Carlson, C. D., Bai, Y., Jonakait, G. M., & Hart, R. P. (1996). Interleukin-1 beta increases leukemia inhibitory factor mRNA levels through transient stimulation of transcription rate. Glia, 18, 141-51. PubMed
Carlson, C. D., & Hart, R. P. (1996). Activation of acidic sphingomyelinase and protein kinase C zeta is required for IL-1 induction of LIF mRNA in a Schwann cell line. Glia, 18, 49-58. PubMed
McCormack, R. J., Hart, R. P., & Ganea, D. (1996). Expression of NK-1 receptor mRNA in murine T lymphocytes. Neuroimmunomodulation, 3, 35-46. PubMed
Ding, M., Hart, R. P., & Jonakait, G. M. (1995). Tumor necrosis factor-alpha induces substance P in sympathetic ganglia through sequential induction of interleukin-1 and leukemia inhibitory factor. Journal of neurobiology, 28, 445-54. PubMed
Kuchinke, W., Hart, R. P., & Jonakait, G. M. (1995). Identification of mRNAs regulated by interferon-gamma in cultured rat astrocytes by PCR differential display. Neuroimmunomodulation, 2, 347-55. PubMed
Liu, C., Bai, Y., Ganea, D., & Hart, R. P. (1995). Species-specific activity of rat recombinant interleukin-1 beta. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 15, 985-92. PubMed
Jonakait, G. M., & Hart, R. P. (1995). Immune cytokine regulation of sympathetic ganglion response to injury. Neuroimmunomodulation, 2, 236-40. PubMed
Ding, M., Hart, R. P., Shadiack, A. M., & Jonakait, G. M. (1994). The interleukin-1-induced increase of substance P in sympathetic ganglia is not mediated by ciliary neurotrophic factor. Journal of neuroscience research, 38, 640-7. PubMed
Harrell, R. A., & Hart, R. P. (1994). Rapid preparation of Thermus flavus DNA polymerase. PCR methods and applications, 3, 372-5. PubMed
Jonakait, G. M., Wei, R., Sheng, Z. L., Hart, R. P., & Ni, L. (1994). Interferon-gamma promotes cholinergic differentiation of embryonic septal nuclei and adjacent basal forebrain. Neuron, 12, 1149-59. PubMed
Shadiack, A. M., Carlson, C. D., Ding, M., Hart, R. P., & Jonakait, G. M. (1994). Lipopolysaccharide induces substance P in sympathetic ganglia via ganglionic interleukin-1 production. Journal of neuroimmunology, 49, 51-8. PubMed
Factor, E. M., Hart, R. P., & Jonakait, G. M. (1993). Neurochemical development of the raphe after continuous prenatal cocaine exposure. Brain research bulletin, 31, 49-56. PubMed
Shadiack, A. M., Hart, R. P., Carlson, C. D., & Jonakait, G. M. (1993). Interleukin-1 induces substance P in sympathetic ganglia through the induction of leukemia inhibitory factor (LIF). The Journal of neuroscience : the official journal of the Society for Neuroscience, 13, 2601-9. PubMed
Hart, R. P., Liu, C., Shadiack, A. M., McCormack, R. J., & Jonakait, G. M. (1993). An mRNA homologous to interleukin-1 receptor type I is expressed in cultured rat sympathetic ganglia. Journal of neuroimmunology, 44, 49-56. PubMed
Riley, L. A., Jonakait, G. M., & Hart, R. P. (1993). Serotonin modulates the levels of mRNAS coding for thyrotropin-releasing hormone and preprotachykinin by different mechanisms in medullary raphe neurons. Brain research. Molecular brain research, 17, 251-7. PubMed
Jonakait, G. M., Ni, L., Walker, P. D., & Hart, R. P. (1991). Development of substance P (SP)-containing cells in the central nervous system: consequences of neurotransmitter co-localization. Progress in neurobiology, 36, 1-21. PubMed
Walker, P. D., Ni, L., Riley, L. A., Jonakait, G. M., & Hart, R. P. (1991). Serotonin innervation affects SP biosynthesis in rat neostriatum. Annals of the New York Academy of Sciences, 632, 485-7. PubMed
Riley, L. A., Walker, P. D., Hart, R. P., & Jonakait, G. M. (1991). Alterations of preprotachykinin (PPT) mRNA in medullary raphe occur following manipulation of serotonin. Annals of the New York Academy of Sciences, 632, 455-6. PubMed
Walker, P. D., Green, T. L., Jonakait, G. M., & Hart, R. P. (1991). A comparison of substance P peptide and preprotachykinin mRNA levels during development of rat medullary raphe and neostriatum. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 9, 47-55. PubMed
Jonakait, G. M., Schotland, S., & Hart, R. P. (1991). Effects of lymphokines on substance P in injured ganglia of the peripheral nervous system. Annals of the New York Academy of Sciences, 632, 19-30. PubMed
Walker, P. D., Riley, L. A., Hart, R. P., & Jonakait, G. M. (1991). Serotonin regulation of neostriatal tachykinins following neonatal 6-hydroxydopamine lesions. Brain research, 557, 31-6. PubMed
Hart, R. P., Shadiack, A. M., & Jonakait, G. M. (1991). Substance P gene expression is regulated by interleukin-1 in cultured sympathetic ganglia. Journal of neuroscience research, 29, 282-91. PubMed
Riley, L. A., Hart, R. P., & Jonakait, G. M. (1991). Both zimelidine and clorgyline decrease preprotachykinin mRNA in adult medullary raphe nuclei. Molecular and cellular neurosciences, 2, 139-44. PubMed
Walker, P. D., Riley, L. A., Hart, R. P., & Jonakait, G. M. (1991). Serotonin regulation of tachykinin biosynthesis in the rat neostriatum. Brain research, 546, 33-9. PubMed
Hart, R. P., Yang, R., Riley, L. A., & Green, T. L. (1991). Post-transcriptional control of tryptophan hydroxylase gene expression in rat brain stem and pineal gland. Molecular and cellular neurosciences, 2, 71-7. PubMed
Jonakait, G. M., Schotland, S., & Hart, R. P. (1990). Interleukin-1 specifically increases substance P in injured sympathetic ganglia. Annals of the New York Academy of Sciences, 594, 222-30. PubMed
Walker, P. D., Schotland, S., Hart, R. P., & Jonakait, G. M. (1990). Tryptophan hydroxylase inhibition increases preprotachykinin mRNA in developing and adult medullary raphe nuclei. Brain research. Molecular brain research, 8, 113-9. PubMed
Green, T. L., & Hart, R. P. (1988). Mutations in poly(A) site downstream elements affect in vitro cleavage activity. Molecular and cellular biology, 8, 1839-41. PubMed
McDevitt, M. A., Hart, R. P., Wong, W. W., & Nevins, J. R. (1986). Sequences capable of restoring poly(A) site function define two distinct downstream elements. The EMBO journal, 5, 2907-13.
Hart, R. P., McDevitt, M. A., & Nevins, J. R. (1985). Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences. Cell, 43, 677-83.
Hart, R. P., McDevitt, M. A., Ali, H., & Nevins, J. R. (1985). Definition of essential sequences and functional equivalence of elements downstream of the adenovirus E2A and the early simian virus 40 polyadenylation sites. Molecular and cellular biology, 5, 2975-83.
Imperiale, M. J., Hart, R. P., & Nevins, J. R. (1985). An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription. Proceedings of the National Academy of Sciences of the United States of America, 82, 381-5.
Hart, R. P., & Folk, W. R. (1982). Structure and organization of a mammalian 5 S gene cluster. The Journal of biological chemistry, 257, 11706-11.
Triezenberg, S. J., Rushford, C., Hart, R. P., Berkner, K. L., & Folk, W. R. (1982). Structure of the Syrian hamster ribosomal DNA repeat and identification of homologous and nonhomologous regions shared by human and hamster ribosomal DNAs. The Journal of biological chemistry, 257, 7826-33.